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Induction of osteogenic differentiation in osteosarcoma cells by poly (ethylene glycol)-coated hydroxyapatite
which is attributed to the stretching vibration of phosphate groups. The sharp absorption band at 3570 cm-1 corresponds to the stretching vibration of OH groups. Based on MTT assay and microscopic images, PEG@HAP nanoparticles increased the proliferation...
Benzothiazole Thiourea Derivatives as Anticancer Agents: Design, Synthesis, and Biological Screening
human breast cancer cells (MCF-7), human
cervix epithelial carcinoma (HeLa), human colon cancer cell line (HT-29), human leukemia cell line
(K-562), and mouse neuroblastoma cell line (Neuro-2a) using cisplatin as a reference by MTT assay...
Studying the Synergistic Effects of Two 15-Lipoxygenase Inhibitors on Apoptosis Induction in PC-3 Cell Line
result to induction of apoptosis. Considering the observed cytotoxic effects of two synthetic 15-LOX-1 inhibitors, 6-Farnesyloxycoumarin (6F) and 4-Farnesyloxycoumarin (4F), synergistic effects of these compounds were studied by MTT assay on a prostate...
بررسی اثر هم افزایی دو ترکیب مهار کننده آنزیم 15- لیپوکسیژناز نوع 1 بر القای مرگ سلولی در رده سلولی DU145
لیپوکسیژنازها آنزیم های بسیار مهمی در متابولیسم لیپیدها می باشند که اسیدهای چرب غیر اشباع را به متابولیت های هیدرو پراکسیدی آنها تبدیل می نمایند. از این بین، اعضای گروه 15- لیپوکسیژناز بر اساس توزیع بافتی و ویژگی های آنزیمی ...
Investigation of cytotoxicity and anti-cancer effects of 7-isopentenyloxycoumarin in vitro
were evaluated after 24, 48 and 72 hours of treatments by MTT assay. The morphological changes
of the nuclei were also observed by DAPI staining. Results showed that 7-isopentenyloxycoumarin
reached its IC50 at concentration of 65 μg/ml after 72...
In vitro investigation of diversin cytotoxicity on 5637 cells
as controls and level of diversin
cytotoxicity was evaluated after 24, 48 and 72 hours of drug administrations, by MTT assay. IC50
of diversin was determined as 70 μg/ml and 40 μg/ml after 48 and 72h of treatment respectively.
Cell death...
Green Synthesis of Iron Nano-particles Using Rosmarinus officinalis Extract and Evaluation the cytotoxic effects against 4T1 and NIH3T3 cell lines
/stabilizing agent was used to detect EL-Fe NPs as well. The potential cytotoxic and anti-proliferative activities of nanoparticles were evaluated on using MTT Assay. Concentrations needed for half-maximal inhibition (IC50s) were calculated using CalcuSyn software...