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Termination of Nociceptive Bahaviour at the End of Phase 2 of Formalin Test is Attributable to Endogenous Inhibitory Mechanisms, but not by Opioid Receptors Activation
%), with intervals of 5 or 60 minutes. In the next set, formalin tests were carried out in companion with injection of Naloxone Hydrochloride, a non-selective antagonist of opioid receptors, pre-formalin injection and 30 and 45 minutes post formalin injection.
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The effect of intrathecal administration of ascorbic acid on chemical pain sensation during formalin test in rat
Ascorbic acid (AA) is an essential micronutrient with acidic pH, it can block a variety of membrane bound receptor proteins including the NMDA site receptors which is important in pain signaling…
The Effects of Intrathecal Administration of hemoglobin on chemical Pain Sensation in Formalin Tests in Rat
and second phase of the formalin test (p<0.01). Same observation was repeated after chronic treatment of hemoglobin also (P<0.001) which was more potent than acute one (p<0.01).
Conclusion. Results of this experiment showed us...
Heated female cannabis sativa flowers hydroalcoholic extract effects on thermal and chemical pain at the level of spinal cord
.t. injection of the extract in 0.01mg/10µl. In order to investigate the chemical pain sensation, formalin test and to evaluate thermal pain threshold, Tail flick test were conducted.
Results: Results: I.t. injection of hydroalchoholic extract...
Chemical pain reduction after administration of Salvia multicaulis extracts in rats
One of the most basic methods for coping with diseases and relieve pain have been the usage of
medicinal plants. Propose of this study is the investigation of analgesic effects of Salvia multicaulis
extract in formalin test...
The effect of Ferula szowitsiana extract on chemical pain in male Wistar rats
Investigations on the use of medicinal plants are appealing to researchers. In Iranian traditional medicine, Ferula szowitsiana is used as an analgesic. This study investigates the effect of the extract of aerial parts of ...
Reduction of chemical pain after intrathecal administration of vitamin K2 in the rats
.
Results. Intrathecal adminis tration of vitamin K2 (20-10-2µg/10µl) in the first and second phases of the formalin test showed a significant decrease in pain (P <0.001, P <0.01), the analgesic effect of dose (2µg/10µl) were higher than the others...
Changes in analgesia and hyperalgesia induced by intraperitoneal administration of morphine in the formalin test during intrathecal administration of Menaquinone-4 in rats
morphine ind uced an algesia/hyp eralgesia in formalin test were investigated in this study.
Materials and method s. The adu lt male Wistar rats (250-300 g) were used. Rats were then sub jected to i.t. surgery. Gro ups inclu de: control, sham...
A comparison between intrathecal and intraperitoneal administrations of Ferula szowitsiana stem and leaves extract on chemical pain in male wistar rats
Study to find pain killers with minimum side effects is one of the researchers interest. In prior
study, analgesic effect of Ferula szowitsiana up to dose of 200mg/kg was seen. In this
investigation ...
INVOLVEMENT OF OPIOIDERGIC AND SEROTONINERGIC SYSTEMS IN THE ANTINOCICEPTIV EEFFECT OF TANACETUM PARTHENIUM
(20mg/kg,
i.p.)(n > 6 in each group).
Pretreatment with naloxane increased pain percepation in the neurogenic phase of
formalin test compared to the control (p<0.001). Moreover cyproheptadine increased
the sensation...