chelator in order to reduce iron concentration seems to be

vital. This study presents the density functional theory calculations of the electronic structure and

equilibrium constant for iron-deferasirox (Fe-DFX) complexes in the gas phase...

The Present research was conducted to evaluate the ability of Deferasirox and Deferiprone (L1) chelators as single and combined therapies in removing lead from biological system. Lead at two doses of 20 (low dose drinking of lead) and 40 mg/kg (high...

in kidneys followed by liver. However, the hypothesis that the two chelators might be more efficient as combined therapy than as single therapy in removing cadmium from the body was considered. In this way, two known chelators deferasirox and deferiprone (L1...

chelators might be more efficient as combined therapy than as single therapy in removing cadmium from the body was considered. In this way, two known chelators Deferasirox (Exjade) and deferiprone (L1) were chosen and tested in the acute rat model. Two...

in high doses can have toxic effects. The aim of this work was to evaluate the hematological changes induced by lead as a toxic metal and characterize the potential efficacy of Deferasirox in removing lead from bodies of male rats.

Methods: Lead...

The Present research was conducted to evaluate the ability of Deferasirox and Deferiprone (L1) chelators as single and combined therapies in removing mercury from biological system. Mercury at two doses of 10 (low dose drinking of mercury) and 30 mg...

The present research aimed to characterize the potential efficiency of Deferasirox in removing thallium after its administration for 30 days following two dose levels of 20 µM and 160 µM of thallium (III) chloride to male Wistar rats everyday. After...

In this work, density functional theory (DFT) study on the electronic structures and binding energies of deferasirox coordinated to Al3+, Fe3+ and Ga3+ metal ions was carried out, using the CAM-B3LYP/6-31G level of the theory in the water...

An investigation was conducted to evaluate the ability of Deferasirox (ICL670 or Exjade) following the distribution of cadmium salt in male Wistar rats. Cadmium was introduced to several groups of weanling male Wistar rats through different means...

The present research aimed to characterize the potential efficiency of deferasirox in removing thallium after its administration for 30 days following two dose levels of 20 and 160 mM of thallium (III) chloride to maleWistar rats every day...