Oxidative effects of long-term onion (Allium cepa) feeding on goat erythrocytes
نویسنده:
, , , , , , ,سال
: 2013
چکیده: Toxic compounds such as disulfides of onions
cause oxidative-induced haemolysis in several animal species.
In order to study the outcomes of long-term onion
consumption on some oxidative haemolysis markers, 12
adult female goats were allocated to three groups, receiving
0% (served as control), 30% (dry matter basis) and 60%
spring-grown onion for 60 days. Blood samples were
obtained before feeding the onion and every 10 days up to
80 days for measuring malonyldialdehyde (MDA), methaemoglobin
(MetHb), mean corpuscular fragility (MCF),
serum-free haemoglobin and serum lactate dehydrogenase
(LDH) and for evaluating their relation to packed cell volume
(PCV) and haemoglobin (Hb) concentrations. PCVand
Hb concentrations reduced, however, remained within reference
ranges in onion-fed goats. MetHb showed a significant
negative correlation with both PCVand Hb (P<0.05) in
onion-fed goats and a significant positive correlation with
MCF and serum-free haemoglobin in goats receiving 30%
onion. MetHb showed a significant positive correlation with
MCF in goats fed with 60% onion. MDA showed a positive
correlation with LDH and serum-free haemoglobin concentrations.
These results suggest a role for oxidative damage in
destructing red cells in goats feeding onions. However, it
seems that up to 60% onions in diet can be consumed by
goats without noticeable clinical anaemia.
cause oxidative-induced haemolysis in several animal species.
In order to study the outcomes of long-term onion
consumption on some oxidative haemolysis markers, 12
adult female goats were allocated to three groups, receiving
0% (served as control), 30% (dry matter basis) and 60%
spring-grown onion for 60 days. Blood samples were
obtained before feeding the onion and every 10 days up to
80 days for measuring malonyldialdehyde (MDA), methaemoglobin
(MetHb), mean corpuscular fragility (MCF),
serum-free haemoglobin and serum lactate dehydrogenase
(LDH) and for evaluating their relation to packed cell volume
(PCV) and haemoglobin (Hb) concentrations. PCVand
Hb concentrations reduced, however, remained within reference
ranges in onion-fed goats. MetHb showed a significant
negative correlation with both PCVand Hb (P<0.05) in
onion-fed goats and a significant positive correlation with
MCF and serum-free haemoglobin in goats receiving 30%
onion. MetHb showed a significant positive correlation with
MCF in goats fed with 60% onion. MDA showed a positive
correlation with LDH and serum-free haemoglobin concentrations.
These results suggest a role for oxidative damage in
destructing red cells in goats feeding onions. However, it
seems that up to 60% onions in diet can be consumed by
goats without noticeable clinical anaemia.
کلیدواژه(گان): Oxidative damage,Erythrocytes,Onion,Goat
کالکشن
:
-
آمار بازدید
Oxidative effects of long-term onion (Allium cepa) feeding on goat erythrocytes
Show full item record
| contributor author | محمد حیدرپور | en |
| contributor author | مریم فخریه | en |
| contributor author | محمدرصا اصلانی | en |
| contributor author | مهرداد مهری | en |
| contributor author | مرتضی کیوانلو | en |
| contributor author | Mohammad Heidarpour | fa |
| contributor author | Mehrdad Mohri | fa |
| contributor author | morteza keywanloo | fa |
| date accessioned | 2020-06-06T13:12:04Z | |
| date available | 2020-06-06T13:12:04Z | |
| date issued | 2013 | |
| identifier uri | http://libsearch.um.ac.ir:80/fum/handle/fum/3345623 | |
| description abstract | Toxic compounds such as disulfides of onions cause oxidative-induced haemolysis in several animal species. In order to study the outcomes of long-term onion consumption on some oxidative haemolysis markers, 12 adult female goats were allocated to three groups, receiving 0% (served as control), 30% (dry matter basis) and 60% spring-grown onion for 60 days. Blood samples were obtained before feeding the onion and every 10 days up to 80 days for measuring malonyldialdehyde (MDA), methaemoglobin (MetHb), mean corpuscular fragility (MCF), serum-free haemoglobin and serum lactate dehydrogenase (LDH) and for evaluating their relation to packed cell volume (PCV) and haemoglobin (Hb) concentrations. PCVand Hb concentrations reduced, however, remained within reference ranges in onion-fed goats. MetHb showed a significant negative correlation with both PCVand Hb (P<0.05) in onion-fed goats and a significant positive correlation with MCF and serum-free haemoglobin in goats receiving 30% onion. MetHb showed a significant positive correlation with MCF in goats fed with 60% onion. MDA showed a positive correlation with LDH and serum-free haemoglobin concentrations. These results suggest a role for oxidative damage in destructing red cells in goats feeding onions. However, it seems that up to 60% onions in diet can be consumed by goats without noticeable clinical anaemia. | en |
| language | English | |
| title | Oxidative effects of long-term onion (Allium cepa) feeding on goat erythrocytes | en |
| type | Journal Paper | |
| contenttype | External Fulltext | |
| subject keywords | Oxidative damage | en |
| subject keywords | Erythrocytes | en |
| subject keywords | Onion | en |
| subject keywords | Goat | en |
| journal title | Comparative Clinical Pathology | fa |
| pages | 195-202 | |
| journal volume | 22 | |
| journal issue | 2 | |
| identifier link | https://profdoc.um.ac.ir/paper-abstract-1033535.html | |
| identifier articleid | 1033535 |