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نمایش تعداد 1-10 از 10
Synthesis, Characterization and In Vitro Antibacterial Evaluation of Novel 4-(1-(Pyrimidin-4-yl)Ethyl)-12H-Pyrimido[4′,5′:5,6][1,4]Thiazino[2,3-b]Quinoxaline Derivatives
A new methodology for the synthesis of 4-(1-(pyrimidin-4-yl)ethyl)-12H-pyrimido[40,50:5,6][1,4]thiazino[2,3-b]quinoxaline derivatives 5a-g was introduced. Condensation of 5-bromo-4-[1-(5-bromo-2,6-dichloropyrimidin-4-yl) ...
Regioselective synthesis of 2-[( E )-(benzo[ d ]thiazol-2(3 H )- ylidene)(cyano)methyl]thiazoles
Cyclocondensation of 2-[bis(methylthio)methylene]malononitrile
and 2-amino-benzenthiol afforded 2-(benzo[ d ]thiazol-2-yl)
malononitrile. This compound, on treatment with phosphorus
pentasulfi de, gave ...
Synthesis of some new pyrimido[4,5-e]tetrazolo[5,1-b][1,3,4]thiadiazine derivatives via an S–N type Smiles rearrangement and their antibacterial evaluation
Several new pyrimido[4,5-e]tetrazolo[5,1-b][1,3,4]thiadiazine derivatives have been synthesised through heterocyclisation of 5-bromo-4,6-dichloropyrimidine with sodium 1-amino-1H-tetrazole-5-thiolate via an S–N type Smiles ...
Synthesis, characterisation, and in vitro antibacterial evaluation of a new class of 2-substituted-4-methyl-7,8-dihydro-5H-pyrimido[4,5-d]thiazolo[3,2-a] pyrimidines
The reaction of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine with 4,5-dihydrothiazol-2-amine in chloroform led to the formation of 2-chloro-4-methyl-7,8-dihydro-5H-pyrimido[4,5-d]thiazolo[3,2-a]pyrimidine (3). The true ...
Study of Toxic Effects of Oxothiazole Derivative as a New Antibacterial Agent
بررسی اثرات سمیت مشتق اکسوتیازول به عنوان یک عامل ضد باکتریایی جدید
گسترش مقاومت باکتریایی در بسیاری از پاتوژنهای مهم انسانی و دامی، سبب افزایش تمایل به شناسایی ترکیبات جدید ضد باکتریایی و اثرات دارویی و سمیت آنها به منظور مهار سویههای مقاوم شده¬است. مشتقات تیازول از ترکیبات جدید ضد ...