Thiazolopyrimidine derivatives have attracted a great deal of interest owing to their antimicrobial [1], antiviral [2] and antitumor [3] activities. In continuation of our previous study on the application of thiazolopyrimidine ...

The reaction of 4-amino-5-bromo-2-chloro-6-methylpyrimidine

( 1 ) with carbon disulfi de in the presence of KOH in

DMF quantitatively gave 5-chloro-7-methylthiazolo[4,5- d ]

pyrimidine-2 (3 H )-thione ...