The insulin-like growth factor I (IGF-IR) plays an essential role in the establishment and maintenance of transformed phenotype. Interference with the IGF-IR pathway by antisense causes reversal of the transformed phenotype ...

Antisense technology is the method of choice for gene therapy and analysis the autocrine function of protein. We have produced a shuttle vector containing a part of GM-CSF cDNA orientated in the antisense direction with ...

Bladder carcinoma cell line 5637 is a transitional cell line which is frequently used as a model for studying various aspects playing role in bladder cancer and as a source of hematopoeitic growth factors. Genetic manipulation ...