Cyclocondensation of 5-amino-6-methyl-2-morpholinopyrimidine-4-thiol (1) and 2-bromo-5,5-dimethylcyclohexane-1,3-dione (2) under mild reaction condition afforded 4,7,7-trimethyl-2-morpholino-7,8-dihydro-5H-benzo[b]pyrimi ...

New derivatives of pyrimido[4,5- e ][1,3,4]oxadiazine were

prepared and their antibacterial evaluations were performed

on four different Gram-negative and Gram-positive bacteria.

Journal of Heterocyclic Chemistry...

Pyrazolo[3,4-d]pyrimidines and related fused heterocyclic compounds are found to have a wide usage as a pharmaceutically important class of compounds for numerous researchers [1]. They exhibit diversified pharmaceutical activities such as antifungal...

Recently the synthesis of fused heterocyclic compounds possessing pyrimidothiazine as

central core has been interested for researchers because of possesing various biological properties such as antibacterial [1], antiallergic, anti...

as precursors in the synthesis of fused ring compounds and novel heterocycle systems. Four novel 6,8-dimethyl-2-(methylthio)-4-(amino substituted)pyrazolo[1,5-α:3,4-dˊ]dipyrimidine were prepared via a multistep synthetic sequence beginning from 4-hydroxy-2,6-bis...

Iodine heterocyclization of 2-amino-4,5-dimethylthiophene-3-carbox- amide with aromatic aldehydes afforded a new series of thieno[2,3-d]pyrimidine derivatives in a single step. Some of these compounds exhibited antimicrobial activities comparable...

Starting from pyrimido[4,5-e][1,3,4]oxadiazines (3a-c), a synthetic pathway to [1,2,4]triazolo[

40,30:1,2]pyrimido[4,5-e][1,3,4]oxadiazines (5a-i) is described. The reaction of pyrimido[4,5-

e][1,3,4]oxadiazines ...

Several derivatives of the new pyridazino[4,3-e][1,3,4]oxadiazine ring system were prepared, and

their antibacterial evaluations were performed on four different Gram-negative and Gram-positive

bacteria.