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RISIn silico prediction of B-cell epitopes of GroEL antigen from Brucella
Brucellosis caused by bacterium Brucella, affecting various domestic and wild species. Economic and medical consequences
of this disease have led to efforts to prevent the infection through the use of vaccines. This ...
Selection of T-cell epitopes from foot-and-mouth disease virus reflects the binding affinity to different cattle MHC class II molecules
The major histocompatibility complex (MHC)-restricted selection of T-cell epitopes of foot-and-mouth disease virus (FMDV) by individual cattle MHC class II DR (BoLA-DR) molecules was studied in a direct MHC-peptide binding assay. By in vitro priming...
Bovine MHC Class II Structure-Function Relationships: Implications for Vaccine Development
T cell mediated immunoregulation plays an important role in protective immunity. The central molecular
interaction, which dictates the selection of the specificity of T cells, depends on the interaction between ...
Bovine MHC Class II Structure-Function Relationships: Implications for Vaccine Development
T cell mediated immunoregulation plays an important role in protective immunity. The central molecular
interaction, which dictates the selection of the specificity of T cells, depends on the interaction between ...
Bovine MHC class II structure-Function relationships: Implications for Genetic Breeding and Vaccine Development
to study whether the selection of the defined T cell epitopes of FMDV in the context of three different BoLA class II haplotypes is mediated by DR molecules. Retro-inverso (RI) peptides, corresponding to the defined T cell epitopes of FMDV were analysed...