In this paper, the dynamic behavior of an immunosuppressive infection model, speci_cally AIDS, is analyzed. We show through a simple mathematical model that a sigmoidal CTL response can lead to the occurrence of transcritical bifurcation...

In this paper, we consider a four dimensional

model of the human immunodeficiency virus-1 (HIV-1)

with delay, which is an extension of some three dimensional

models. We approach the treatment problem ...

Developing accurate mathematical models for host immune response in immunosuppressive

diseases such as HIV and HTLV-1 are essential to achieve an optimal drug therapy

regime. Since for HTLV-1 specific CTL response typically occurs...