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RISThiazolo[4,5- d ]pyrimidines: synthesis and antibacterial evaluation
The reaction of 4-amino-5-bromo-2-chloro-6-methylpyrimidine
( 1 ) with carbon disulfi de in the presence of KOH in
DMF quantitatively gave 5-chloro-7-methylthiazolo[4,5- d ]
pyrimidine-2 (3 H )-thione ...
Synthesis of various derivatives of [1,3]selenazolo[4,5-d]pyrimidine as a novel selenazolocondenced heterocyclic system
triethylorthoesters to yield various derivatives of a novel heterocyclic system of [1,3]selenazolo[4,5-d]pyrimidine 3 (a-i) in excellent yields with potential biological activities....
New access to thiazolo[4,5-d]pyrimidine derivativess
with various isothiocyanates in the presence of sodamide in DMF to form the new thiazolo[4,5-d] pyrimidine derivatives....
Synthesis of novel highly fluorescent of triazolo pyrimido[4,5-d] pyrimidin-4(1H)-one derivatives
The pyrimidine ring system undoubtedly belongs to the most important heterocycles in nature, as it represent the main structure of many biologically active compounds, including nucleosides and nucleotides.[1-3] This ...
Synthesis of Various Derivatives of a Novel Heterocyclic System of Tetrazolo[1,5-a][1,2,3]triazolo[4,5-d]pyrimidine
-chloro-3-alkyl-7-methyl-3H-
[1,2,3]triazolo[4,5-d]pyrimidine (2a-e). Further reaction of compounds (2a-e) with NaN3 in
EtOH was resulted in various derivatives of novel heterocyclic system of tetrazolo[1,5-
a][1,2,3]triazolo[4,5-d]pyrimidine...