) strategy for 16 selection

rounds to generate an enriched pool of aptamers that

specifically recognize the HER2 positive cell line. During the

Cell SELEX procedure, a human HER2-overexpressing breast

cancer cell line and a human...

called Cell SELEX was employed to enrich DNA aptamers that are

able to identify HER2 positive cells and HER2 protein in its natural

conformation. In this paper we have addressed main challenges for

the cell SELEX technique. We have also...