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Bacterial Ghosts: a promising candidate for vaccine development against gram-negative bacteria and delivery of molecular vaccines against poultry diseases
demand for new strategy to fight against these diseases. Bacterial Ghosts (BGs) are safe non-living, empty envelopes, perfectly mimicking the Gram-negative bacteria from which they are derived. They are produced by controlled expression of coliphage ɸX174...
Immune dynamics of chicken macrophage-like monocytes following exposure to bacterial ghosts loaded with M2e segment and NP gene as a universal DNA vaccine against avian influenza
investigated the
effect of a DNA vaccine based on the external domain of Matrix protein (M2e) and nucleoprotein
(NP) gene, which was loaded into E.coli Top10 and O78 K80 bacterial ghosts on the expression
profile of pro...
Use of bacterial ghosts as novel drug delivery systems to improve cancer treatment
Introduction: The bacterial ghost (BG) system represents a novel
and progressive approach in the development of bacterial mediated
cancer immunotherapy. The empty inner space of BGs can be filled
with drugs, proteins, DNA...
Lattice Boltzmann With Ghost Flow Method For Curve Boundary In Simulation Aerodynamic Force Around Airfoil
In this paper, a ghost flow in lattice Boltzmann method is developed to simulate for curved boundaries. As such, a new formulation for airfoil boundary. Conditions is developed using a bilinear interpolation method. In this researched have been...
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Bacterial ghost of avian pathogenic E. coli (APEC) serotype O78:K80 as a homologous vaccine against avian colibacillosis
vaccines for this disease, particularly
because it is notoriously difficult to make a vaccine that contains all the contributing pathogenic bacteria. Here, we report the design and fabrication of a bacterial ghost (BG) of E. coli
O78:K80...
In vitro studies to develop a bacterial ghost of avian pathogenic E.coli (APEC) serotype 078 as a non-viable oral and parentral vaccine against avian colibacilosis
viable cell count, during 6 hours of induction. Bacterial ghost construction was confirmed by scanning electron microscopy and CFU de ermination.
Results & Conclusion: The plasmid (pmET32a) was used to transform a wild-type E.coli serotype...
Production of Bacterial Ghost from Avian Pathogenic E-Coli (APEC), O2K1 Serotype
.coli are pathogenic in poultry.
One of the major avian pathogenic serotypes is E. Coli O2K1, that is responsible for colisepticemia
in poultry flocks. The aim of this project was to produce a bacterial ghost of E. coli O2 in order to...
Use of Bacterial Ghosts as Novel Drug Delivery Systems to Improve Cancer Treatment
micro- and nanoparticles, liposomal
systems and erythrocyte ghosts have been developed. Bacterial ghosts (BG) represent novel
advanced delivery and targeting vehicles suitable for delivery of hydrophobic or watersoluble
drugs. BGs...