calorimetry

and spectrophotometry, respectively. The size of the micelles was determined with a light scattering

method. In vitro drug release studies were carried out using naltrexone hydrochloride and vitamin B12

as model drugs. The rate...

An in-situ forming implant formulation of naltrexone (NTX) was achieved based on a minimum initial burst release of NTX in the in-vitro release medium using a Box-Behnken design. Variables such as percent of copolymer by weight, copolymer...