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RISSynthesis of new derivatives of pyridazino[4,3-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
of cyclic nucleotide phosphodiesterase[2], dyestuff [3], and precursors of herbicides [4]. In continuation of our interest in chemistry of fused heterocycles of pharmacological importance and exploration of their synthetic pathways, we decided to synthesize...
Synthesis of new derivatives of pyrimido[4,5-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
The reaction of 1-amino-2-mercapto-5-methyl-1,2,3-triazole with 4-amino-5-methyl-4H-1,2,4-triazole-3-thiol in the presence of Et3N in CH3CN gave quantitatively 3-[(5-bromo-2-chloro-6-methyl-4-pyrimidinyl)sulfanyl]-5-methyl-4H-1,2,4-triazol-4-amine...
Synthesis of New Derivatives of Pyrimido[4,5-e][1,2,4]triazolo[4,3b][1,2,4]triazine
and especially fused triazines are also an important class of heterocyclic compounds with antifungal and antibacterial activities3,4. In continuation of our interests in the application of pyrimidine moiety in the synthesis of new heterocyclic compounds, compound...
A general synthesis of new derivatives of pyrimido[4,5-e][1,2,4]triazolo[3,4-b] [1,3,4]thiadiazine
pyrimido[4,5-e][1,2,4]-triazolo[3,4-
b][1,3,4]-thiadiazine-7,9-diones have been synthesized by the condensation of 3-alkyl-4-
amino-5-mercapto-[1,2,4]-triazoles with 5-bromobarbituric acid.[2]
In continuation of our previous efforts...
Soliton-potential interaction in the phi4 model
A model for the soliton-potential scattering is presented. This model is constructed with a better approximation for adding the potential to the Lagrangian through the metric of background space time. The results of the ...
Synthesis of pyrimido[4,5-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine as a Novel heterocyclic system
-2].Moreover, tetrazoles have found
utility in pharmaceuticals as lipophilic spacers and carboxylic acid surrogates, in special
explosives, photography and information recording systems[3]. Herein, 2,4-dichloro-
5(chloromethyl)-6...
Tautomerization and intramolecular hydrogen bond strength of 1-(4- Chlorophenyl)-4,4,4-trifluorobutane-1,3-dione by quantum calculations and experimental spectroscopy
Two stable cis-enol forms can be drawn for p-Cl-TFBA and TFBA,
the structure and their relative stabilities, calculated at B3LYP/6-311++G** level of theory, are
show in Fig.1. The relative stabilities for the ...
Condensation of dithizone analogues with 4, 5 dihalopyrimidinpyrimido[5, 4-e][1,3,4] thiadiazines or pyrimido[4, 5-e][1,3,4]
pyrimido[5, 4-e][1,3,4] thiadiazines or pyrimido[4, 5-e][1,3,4] thiadiazines?...
Facile Synthesis of New [1,2,4]Triazolo[4,3-b]pyridazine
A number of new [1,2,4]triazolo[4,3-b]pyridazines were prepared by either cyclocondesation of
substituted hydrazinopyridazines with orthoesters or oxidative cyclization of their hydrazone analogs in
nitrobenzene as an oxidizing agent...
Competitive Bulk Liquid MembraneTransport of Transition and Post Transition Metal Cations Using (2, 3-Diphenylquinoxaline)-4،4
of cobalt(II), nickel (II), cupper (II), zinc (II), silver (I) and lead(II) metal cations and the source and receiving phases being buffered at pH=4.9 and pH=3, respectively. The membrane phase incorporated a new synthesized ionophore, (2...